Andrei, L. This study included eight cases of inpatients diagnosed by echography and NMR with testicular tumors. The age of patients was between 46 and 81 with a mean of The tumors were unilateral, with disease limited to testicle and accompanied by pain except one case with bone involvement.
Orchectomy was performed as first therapeutic and diagnostic purpose.
Cancer Learn about Neuroendocrine tumors Cancerul pancreatic Neuroendocrine cancer incidence This type of cancer has a high mortality, and the overall survival is also low.
A standard chemotherapy protocol has not been used because of reduced number of patients. Microscopy revealed in all cases a stromal proliferation with medium size cells, monomorphic shape and prominent nucleoli. Alphafetoprotein was positive in seminal tubes and negative in tumor, NK1 in small lymphocyte and negative in tumor and L26 diffuse positive in tumor.
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CLA diffuse positive in tumor. We were able to follow up only four patients. Conclusions: The diagnosis was of NHML in six cases and for two secondary involvement of hematopoietic malignancy myeloid sarcoma and leukemia.
Unfavorable evolution with 6 months relapse and one death prove a more aggressive evolution of primitive testicular lymphoma. Cytokinic panel in rheumatoid arthritis and correlation with histological patterns of synovitis - active type of disease Carmen Avramescu, C. Vere, Cl. Margaritescu, Adriana Turculeanu, Maria Balasoiu, Suzana Rogoz Rheumatoid arthritis RA is a chronically inflammatory disease of the articular synovial, with severe, progressive and irreversible articular destruction.
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We want to determine certain pro-inflammatory cytokines tumoral-alpha - TNF-alpha necrosis factor, interleukine-6 - IL-6, interleukine-8 - IL-8anti-inflammatory cytokines interleukine - IL and immunomodulators interleukin-2 - IL-2 in some RA patients serum at the active stage of the disease and correlation with histological patterns of synovitis - active type of disease.
Material and methods. From the 37 patients clinical investigated only 12 were histopathological examined. The serum levels of IL-2 have been found low in patients with RA in the active stage of the disease, the lowest values having been determined at the patients in the 3rd stage of the disease, who also have the highest values of pro-inflammatory cytokines.
In the case of IL the lowest values have been found at patients in the advanced stages of the disease.
In the serum of RA patients with follicular synovitis TNF-alpha was a dominant cytokine compared to patients with diffuse disease, but the greatest serum level was found in patient with granulomatous synovitis. Concentrations of IL-6 and IL-2 were highest in the serum of RA patients with follicular synovitis in comparison to patients with diffuse synovitis and could distinguish RA patients with these two histological variants of the disease.
In the active stage of the disease, the symptoms are a consequence of the interleukin pro and anti-inflammatory game: high serum levels of pro-inflammatory cytokines are accompanied by low serum levels of anti-inflammatory cytokines.
Cytokines can be used as monitorization markers of the acutization period in RA, increase in serum levels of pro-inflammatory cytokines showing the progression from the inactive phase to a new period of activity pancreatic cancer etiology the disease. The association between distinct histological appearance of rheumatoid synovitis and serum cytokine profile and diverse clinical activity of disease seems to confirm its heterogeneity.
The pathomechanism of sudden infant death syndrome SIDS pancreatic cancer etiology nemathelminthes phylum been clarified yet. The high rate of early progenitor cells in carotid body has been reported as a pathognomic feature for SIDS.
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Aim and Study design. A comparison was made between the rates of dark and early progenitor cells. Outcome measures. Results and conclusion.
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In this study on Hungarian SIDS cases, we confirmed the observation that infants who died suddenly have an underdeveloped carotid body. Pancreatic cancer etiology invasive mammary cancer is the most frequent malign tumor of a woman. Among the potential prognostic factors are included the biomarkers which measure or are associated with biological processes involved in the tumoral progression.
We study the prognostic importance of the c-erbB2 oncoprotein in the invasive mammary cancer. We included in the study 56 female patients suffering of invasive mammary cancer. The tissue fragments were fitted in formalin, included to paraffin, detoxifierea organismului acasă colored Hematoxylin-Eosin HE ; toxina clostridium the determination of the c-erbB2 we used the immunohistochemical method of Avidin-Biotin complex ABC.
From the total of 56 tumors, 38 The positivity of c-erbB2 oncoprotein was correlated with the size of the tumor; the carcinomas which are not infiltrative ductal, knows as pancreatic cancer etiology a better prognostic, were c-erbB2 negative. The place and the role of histological examination in diagnostic algorithm of urinary system tuberculosis Em. Trasca, E. Trasca, R.
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- To pancreatic cancer etiology the frequency of KRAS mutations in a cohort of Romanian patients, we performed Sanger sequencing for exon 2 and exon 3 of the gene [ Adjuvant chemotherapy role is thus essential in the attempt to downstage the tumoral grade.
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Buzulica, Gh. Dragoi, Iuliana Nicolescu The diagnosis of tuberculosis of renal and urinary tract is made by identifying Koch bacillus in special cultures and using histological examination of surgical removed pieces. Not in all cases, the usual pathological techniques are very specific.
Using special stain for acid-fast bacilli it can be certified the etiological diagnostic. All the surgical removed pieces were studied using usual pathology methods. In order to find renal tuberculosis we performed on surgical pieces special staining Ziehl-Nielsenwe noted the pathological finding in each case and we found seven cases with certainly tuberculosis etiology.
A rare case of glioblastoma multiforme I. Radu, A. Nicola, Daniela Micu, D.
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Minea A male, 39 years, enters rapidly in coma, is admitted in the Neurological Hospital Brasov and deceases after 4 hrs. At necropsy, macroscopic appearances of the cut surface showing unique tumor mass in all brain from frontal lobe to cerebellum, with extensive cortical invasion.
The tumor has a variable coloration, a yellowish central necrosis and cystis containing turbid fluid. Histopathological aspect is extremely variable with regional heterogeneity: striking cellular pleomorphism with a lack of cell processes, anaplastic glial cells, and some multinucleated giant cells, large necrotic areas with pseudopalisading of surrounding tumor cells and microvascular proliferation, as glomeruloid tufts. Neurofibroma, schwannoma or a hybrid tumor of the peripheral nerve sheath?
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Elena Doina Murarescu, Luminita Ivan, Maria Sultana Mihailovici Classically, the different subtypes of the peripheral nerve sheets tumors display typical morphological features, which differentiate them from the other nervous tumors.
Either schwannoma or neurofibromma have characteristic histological and immunohistochemical features. We present a case of peripheral nerve sheets hybrid tumor, which have had histological and immunohistochemical features of neurofibroma and schwannoma. Niculescu, V. Jinga, Carmen Diaconu, Lorelei Brasoveanu The aim of this study was to evaluate regulatory cell cycle factors in juxta-tumoral renal parenchyma in order to obtain information regarding early primary changes occurred in normal renal cells.
Specimens of juxta-tumoral renal parenchyma were harvested from the tumoral kidney in 10 patients with no history of treatment before surgery.